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Microinfarction in Classic Migraine? A Study with Magnetic Resonance Imaging Findings Stroke 22:1010-1014, Ferbert,A.,et al, 1991 See this aricle in Pubmed Article Abstract By means of magnetic resonance imaging we investigated a total of 45 patients suffering from classic migraine;25 patients had been treated in our department for classic migraine over the past 2 years(group A),and 20 other patients investigated between 1976 and 1984 were reexamined for this study(group B).Thirty-two age-and roughly sex-matched healthy volunteers underwent magnetic resonance imaging and served as controls(group C).There was a trend for patients with classic migraine to have more subcortical patchy lesions on T2-weighted magnetic resonance imaging.In a comparison of our control subjects and patients with a history of>20 attacks of classic migraine taken from groups A and B,this difference in number of lesions was significant(p=0.02).The results suggest that patchy lesions in patients with classic migraine should be interpreted with particular caution before diagnosing a demyelinating disease since the lesions could be ischemic in origin.

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